PXD059190

PXD059190 is an original dataset announced via ProteomeXchange.

Title	Quantitative proteomics of cytokine-induced memory-like (CIML) NK cells
Description	NK cells from healthy donors were isolated from peripheral blood and stimulated overnight with IL-12/15/18 to induce a memory-like phenotype. After 7 days of culture, the phenotype and degranulation potential of CIML NK cells was characterized in two distinct NK cell subsets: CD16+/CD56+ and CD16−/CD56. Finally, NK cell subsets were purified using fluorescence-activated cell sorting (FACS) and subjected to high-throughput multiplexed quantitative proteomics.
HostingRepository	PRIDE
AnnounceDate	2025-07-14
AnnouncementXML	Submission_2025-07-14_03:29:15.659.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Inmaculada Jorge
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Eclipse

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-23 09:37:57	ID requested
⏵ 1	2025-07-14 03:29:16	announced

Dataset with its publication pending

submitter keyword: LC-MSMS, CD16+CD56+, iTRAQ8plex isobaric labeling, quantitative proteomics,CIML NK cells, CD16−CD56+

Jesús María Vázquez Cobos
contact affiliation	Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid.
contact email	jvazquez@cnic.es
lab head
Inmaculada Jorge
contact affiliation	Cardiovascular Proteomics Lad. Spanish National Center for Cardiovascular Research (CNIC). Madrid.
contact email	ijorge@cnic.es
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD059190

PRIDE project URI

• PRIDE
  1. PXD059190
     1. Label: PRIDE project
     2. Name: Quantitative proteomics of cytokine-induced memory-like (CIML) NK cells