PXD059164 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Top-down murine MMTV-PyMT proteoform landscape |
| Description | We developed a top-down proteomic approach to characterize late-stage, primary tumor tissues harvested from MMTV-PyVT mice. This methodology allowed us to expand the coverage for high MW proteoforms using a murine model of breast cancer. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-03-16 |
| AnnouncementXML | Submission_2026-03-16_03:47:38.003.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Suzanne Ponik |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | phosphorylated residue; acetylated residue |
| Instrument | maXis |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2024-12-22 21:09:11 | ID requested | |
| ⏵ 1 | 2026-03-16 03:47:39 | announced | |
Publication List
| Knott SJ, Tucholski T, Josyer H, Inman D, Friedl A, Zhu Y, Ge Y, Ponik SM, Deciphering Proteoform Landscape of Mammary Carcinoma by Top-Down Proteomics. J Proteome Res, 24(3):1425-1438(2025) [pubmed] |
| 10.1021/acs.jproteome.4c01044; |
Keyword List
| ProteomeXchange project tag: Cancer (B/D-HPP) |
| submitter keyword: post-translational modifications, 2D-SEC-RPC-MS, high molecular weight proetoforms,breast cancer, proteoform, MMTV-PyMT tumors |
Contact List
| Ying Ge |
|---|
| contact affiliation | Professor, University of Wisconsin-Madison |
| contact email | ying.ge@wisc.edu |
| lab head | |
| Suzanne Ponik |
|---|
| contact affiliation | University of Wisconsin-Madison |
| contact email | ponik@wisc.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD059164 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD059164
- Label: PRIDE project
- Name: Top-down murine MMTV-PyMT proteoform landscape
