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PXD059152

PXD059152 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteome profiling of Candida albicans
DescriptionThe complex ecological dynamics between Streptococcus mutans and Candida albicans within dental plaque biofilms play a pivotal role in the etiology of dental caries. To investigate the "contact-independent" interactions between these two species, we developed a transwell co-culture system. Utilizing quantitative proteomics profiling, we aimed to dissect the impact of S. mutans on the proteomics profile of C. albicans and to uncover the molecular mechanisms that regulate their interaction. These results underscore the profound changes in the proteomics landscape of C. albicans in response to co-cultivation with S. mutans. Our study offers novel insights into the functional interplay between these predominant constituents of dental plaque, shedding light on their role in oral microbial ecology and the pathogenesis of dental caries.
HostingRepositoryPRIDE
AnnounceDate2025-01-25
AnnouncementXMLSubmission_2025-01-25_00:04:56.145.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYixin Zhang
SpeciesList scientific name: Candida albicans (Yeast); NCBI TaxID: 5476;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive Plus
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-12-22 20:39:40ID requested
12025-01-25 00:04:56announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Candida albicans, Streptococcus mutans, LC-MS/MS
Contact List
Dr Peng Xian
contact affiliationState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China (lab head)
contact email2020224035084@stu.scu.edu.cn
lab head
Yixin Zhang
contact affiliation15982217725
contact email2020224035084@stu.scu.edu.cn
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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