PXD059115 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | HOXB13 interactome in prostate cancer PC3 cell line |
| Description | Transcription factors are one of the major groups of proteins whose suppression leads to tumor growth arrest. Different types of cancer express a specific set of transcription factors that establish and maintain specific gene expression patterns. In prostate cancer cells, one of the key transcriptional regulators is the HOXB13 protein, but its function has not been well characterized. In the present study, we searched for protein partners of HOXB13 by co-immunoprecipitation followed by high-throughput mass spectrometric analysis (IP/LC-MS) using the PC3 cell line as a source. This analysis revealed that the major partners of HOXB13 were transcription factors with different types of DNA-binding domains. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-11-06 |
| AnnouncementXML | Submission_2025-11-05_22:56:19.123.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Rustam Ziganshin |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2024-12-21 07:24:57 | ID requested | |
| ⏵ 1 | 2025-11-05 22:56:19 | announced | |
Publication List
Keyword List
| submitter keyword: Human, PC3 cell line, LC-MS, HOXB13, prostate cancer |
Contact List
| Maksim Erokhin |
|---|
| contact affiliation | Institute of Gene Biology, Russian Academy of Sciences, Group of Chromatin Biology |
| contact email | yermaxbio@yandex.ru |
| lab head | |
| Rustam Ziganshin |
|---|
| contact affiliation | Shemyakin-Ovchinnikov Institute of bioorganic chemistry Russian Academy of Sciences |
| contact email | rustam.ziganshin@gmail.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/11/PXD059115 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD059115
- Label: PRIDE project
- Name: HOXB13 interactome in prostate cancer PC3 cell line
