PXD059074

PXD059074 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Mapping the Proteomic Landscape of Pancreatic Cancer: Prognostic Insights and Subtype Stratification
Description	We conducted a comprehensive proteomic analysis on 115 PDA patient samples, with matched adjacent normal tissue and comprehensive clinical and molecular data. Differential abundance and pathway analyses identified upregulated proteins and pathways within key subgroups. Unsupervised consensus clustering was used to establish a proteomic-based classification of PDA subtypes. A protein-based risk score was developed and validated using a series of multicox regression analyses with LASSO regularization.
HostingRepository	PRIDE
AnnounceDate	2025-09-30
AnnouncementXML	Submission_2025-09-29_21:39:22.180.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zainab Noor
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	TripleTOF 6600

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-19 23:18:40	ID requested
⏵ 1	2025-09-29 21:39:22	announced

Publication List

10.1158/2767-9764.CRC-25-0229;

10.1158/2767-9764.CRC-25-0229;

Keyword List

submitter keyword: Survival analysis, Signature, Human,Pancreatic, Prognostic, SWATH-MS

submitter keyword: Survival analysis, Signature, Human,Pancreatic, Prognostic, SWATH-MS

Contact List

Adel T Aref
contact affiliation	ProCan Oncology - Children’s Medical Research Institute
contact email	aaref@cmri.org.au
lab head
Zainab Noor
contact affiliation	ProCan, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, New South Wales, Australia
contact email	znoor@cmri.org.au
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD059074
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD059074

PRIDE project URI

Repository Record List

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