PXD059037

PXD059037 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Phosphochromatome profiling of C-terminally truncated CDK6
Description	Pre/pro-B-cell lines were generated from bone marrow cells of Cdk6-/- mice by retroviral overexpression of the BCR-ABL (p185) fusion oncogene. These cell lines were transduced with constructs expressing HA-tagged versions of wildtype Cdk6 or of a C-terminally truncated variant of Cdk6 (HA-Cdk6-ΔC). Given the role of CDK6 in transcriptional regulation, we studied the phosphorylation of proteins associated with the chromatin (the phosphochromatome) using phospho-proteomics in cell lines that expressed C-terminally truncated CDK6, wildtype CDK6, or that had a CDK6 knock-out.
HostingRepository	PRIDE
AnnounceDate	2024-12-19
AnnouncementXML	Submission_2024-12-19_01:26:24.920.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD059037
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Thorsten Klampfl
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	phosphorylated residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-19 00:36:44	ID requested
⏵ 1	2024-12-19 01:26:25	announced

Publication List

10.6019/PXD059037;

10.6019/PXD059037;

Keyword List

submitter keyword: cycline dependent kinase 6, C-lobe

submitter keyword: cycline dependent kinase 6, C-lobe

Contact List

Karoline Kollmann
contact affiliation	University of Veterinary Medicine Vienna Department of Biological Sciences and Pathobiology Pharmacology and Toxicology
contact email	karoline.kollmann@vetmeduni.ac.at
lab head
Thorsten Klampfl
contact affiliation	University of Veterinary Medicine Vienna Pharmacology and Toxicology Veterinaerplatz 1 1210 Vienna
contact email	thorsten.klampfl@vetmeduni.ac.at
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/12/PXD059037
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/12/PXD059037

PRIDE project URI

Repository Record List

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