PXD059021

PXD059021 is an original dataset announced via ProteomeXchange.

Title	Proteomic analysis of proteins interacting with MacroD1 in the mouse heart
Description	Sepsis-Induced Myocardial Injury (SIMI) is a severe form of cardiac dysfunction that involves multiple mechanisms, including inflammatory damage and mitochondrial injury . Our research has demonstrated that MacroD1 plays a significant role in SIMI. By employing liquid chromatography-mass spectrometry (LC-MS) analysis to investigate the interactome of MacroD1, we have explored the mechanisms by which MacroD1 is involved in the pathogenesis of SIMI
HostingRepository	iProX
AnnounceDate	2024-12-19
AnnouncementXML	Submission_2025-09-11_20:12:51.419.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xiaoqiang Chen
SpeciesList	scientific name: Mus ; NCBI TaxID: 10088;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-18 19:42:41	ID requested
1	2025-06-22 18:55:21	announced
⏵ 2	2025-09-11 20:12:52	announced	2025-09-12: Add info.

Chen X, Yuan T, Zheng D, Li F, Xu H, Ye M, Liu S, Li J, Cardiomyocyte mitochondrial mono-ADP-ribosylation dictates cardiac tolerance to sepsis by configuring bioenergetic reserve in male mice. Nat Commun, 16(1):8119(2025) [pubmed]

submitter keyword: Mouse heart MacroD1 LC-MSMS

Jun Li
contact affiliation	Department of Cardiology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine
contact email	junli@shsmu.edu.cn
lab head
Xiaoqiang Chen
contact affiliation	Xiamen Cardiovascular Hospital School of Medicine，Xiamen University
contact email	chenxiaoqiang39@163.com
dataset submitter

iProX dataset URI