PXD058991

PXD058991 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Protein interaction partners of C. elegans cap-specific mRNA (nucleoside-2'-O-)-methyltransferases CMTr-1 and CMTR-2.
Description	RNA epigenetic modification at cap-adjacent 2’-O-ribose methylation (cOMe), which occurs on the first and second transcribed nucleotides of RNAs is highly conserved and is catalysed by the cap-adjacent methyltransferases CMTr1 and CMTR2 and We are studying CMTr-1 and CMTr-2 in C. elegans. Immunoprecipitation of endogenous, GFP-tagged CMTr-1 and CMTR-2 proteins reveal that CMTr-1 affinity purifies with splicing factors, RNA processing factors and RNA binding proteins.
HostingRepository	PRIDE
AnnounceDate	2025-04-30
AnnouncementXML	Submission_2025-04-30_04:48:59.296.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Berndt Muller
SpeciesList	scientific name: Caenorhabditis elegans; NCBI TaxID: 6239;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-18 07:13:37	ID requested
⏵ 1	2025-04-30 04:48:59	announced

Publication List

10.1101/2025.03.10.638824;

10.1101/2025.03.10.638824;

Keyword List

submitter keyword: Nematodes, immunoprecipitation, LC-MS/MS

submitter keyword: Nematodes, immunoprecipitation, LC-MS/MS

Contact List

Berndt Muller
contact affiliation	School of Medicine, Medical Sciences and Nutrition Institute of Medical Sciences University of Aberdeen Foresterhill Aberdeen AB25 2ZD Scotland UK
contact email	b.mueller@abdn.ac.uk
lab head
Berndt Muller
contact affiliation	University of Aberdeen
contact email	b.mueller@abdn.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/04/PXD058991
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/04/PXD058991

PRIDE project URI

Repository Record List

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