PXD058967

PXD058967 is an original dataset announced via ProteomeXchange.

Title	Multi-omics analysis reveals the sensitivity of immunotherapy for unresectable non-small cell lung cancer
Description	Peripheral blood plasma was collected from unresectable stage III and IV non-small cell lung cancer patients who were negative for driver mutations before receiving immunotherapy. Then we classified samples according to the follow-up results after two courses of immunotherapy and non-targeted metabolomics and proteomics analyses were performed to select different metabolites and proteins. Finally, potential biomarkers were picked out by applying machine learning methods including random forest and stepwise regression and prediction models were constructed by logistic regression.
HostingRepository	iProX
AnnounceDate	2024-12-18
AnnouncementXML	Submission_2025-05-19_00:11:13.793.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Rui Wu
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-17 22:44:14	ID requested
⏵ 1	2025-05-19 00:11:14	announced

Wu R, Wei K, Huang X, Zhou Y, Feng X, Dong X, Tang H, Multi-omics analysis reveals the sensitivity of immunotherapy for unresectable non-small cell lung cancer. Front Immunol, 16():1479550(2025) [pubmed]

submitter keyword: Non-small cell lung cancer, Immune checkpoint inhibitors, Metabolomics, Proteomics, Prediction models

Xin Dong
contact affiliation	School of Medicine, Shanghai University
contact email	dongxin@shu.edu.cn
lab head
Rui Wu
contact affiliation	Peking University Cancer Hospital & Institute
contact email	ruiwu@bjmu.edu.cn
dataset submitter

iProX dataset URI