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PXD058967

PXD058967 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMulti-omics analysis reveals the sensitivity of immunotherapy for unresectable non-small cell lung cancer
DescriptionPeripheral blood plasma was collected from unresectable stage III and IV non-small cell lung cancer patients who were negative for driver mutations before receiving immunotherapy. Then we classified samples according to the follow-up results after two courses of immunotherapy and non-targeted metabolomics and proteomics analyses were performed to select different metabolites and proteins. Finally, potential biomarkers were picked out by applying machine learning methods including random forest and stepwise regression and prediction models were constructed by logistic regression.
HostingRepositoryiProX
AnnounceDate2024-12-18
AnnouncementXMLSubmission_2025-05-19_00:11:13.793.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterRui Wu
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-12-17 22:44:14ID requested
12025-05-19 00:11:14announced
Publication List
Wu R, Wei K, Huang X, Zhou Y, Feng X, Dong X, Tang H, Multi-omics analysis reveals the sensitivity of immunotherapy for unresectable non-small cell lung cancer. Front Immunol, 16():1479550(2025) [pubmed]
Keyword List
submitter keyword: Non-small cell lung cancer, Immune checkpoint inhibitors, Metabolomics, Proteomics, Prediction models
Contact List
Xin Dong
contact affiliationSchool of Medicine, Shanghai University
contact emaildongxin@shu.edu.cn
lab head
Rui Wu
contact affiliationPeking University Cancer Hospital & Institute
contact emailruiwu@bjmu.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI