PXD058967
PXD058967 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Multi-omics analysis reveals the sensitivity of immunotherapy for unresectable non-small cell lung cancer |
Description | Peripheral blood plasma was collected from unresectable stage III and IV non-small cell lung cancer patients who were negative for driver mutations before receiving immunotherapy. Then we classified samples according to the follow-up results after two courses of immunotherapy and non-targeted metabolomics and proteomics analyses were performed to select different metabolites and proteins. Finally, potential biomarkers were picked out by applying machine learning methods including random forest and stepwise regression and prediction models were constructed by logistic regression. |
HostingRepository | iProX |
AnnounceDate | 2024-12-18 |
AnnouncementXML | Submission_2025-05-19_00:11:13.793.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Rui Wu |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | timsTOF Pro |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2024-12-17 22:44:14 | ID requested | |
⏵ 1 | 2025-05-19 00:11:14 | announced |
Publication List
Wu R, Wei K, Huang X, Zhou Y, Feng X, Dong X, Tang H, Multi-omics analysis reveals the sensitivity of immunotherapy for unresectable non-small cell lung cancer. Front Immunol, 16():1479550(2025) [pubmed] |
Keyword List
submitter keyword: Non-small cell lung cancer, Immune checkpoint inhibitors, Metabolomics, Proteomics, Prediction models |
Contact List
Xin Dong | |
---|---|
contact affiliation | School of Medicine, Shanghai University |
contact email | dongxin@shu.edu.cn |
lab head | |
Rui Wu | |
contact affiliation | Peking University Cancer Hospital & Institute |
contact email | ruiwu@bjmu.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |