PXD058857

PXD058857 is an original dataset announced via ProteomeXchange.

Title	ARID1A-induced transcriptional reprogramming rewires signalling responses to drug treatment in melanoma
Description	Proteomic study studying how ARID1A-mediated transcriptional rewiring drives resistance to MAPK inhibitors in melanoma by altering signalling pathways, immune interactions, and receptor dynamics, highlighting potential targets for combinatorial therapies.
HostingRepository	PRIDE
AnnounceDate	2025-01-14
AnnouncementXML	Submission_2025-01-14_06:12:26.592.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Evangelia Petsalaki
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-13 08:09:43	ID requested
⏵ 1	2025-01-14 06:12:26	announced

10.1101/2024.12.05.626952;

submitter keyword: drug resistance,melanoma, phosphoproteomics

Evangelia Petsalaki
contact affiliation	EMBL-EBI, Wellcome Genome Campus, CB10 1SD, Hinxton
contact email	petsalaki@ebi.ac.uk
lab head
Evangelia Petsalaki
contact affiliation	EMBL-EBI
contact email	petsalaki@ebi.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/01/PXD058857

PRIDE project URI

• PRIDE
  1. PXD058857
     1. Label: PRIDE project
     2. Name: ARID1A-induced transcriptional reprogramming rewires signalling responses to drug treatment in melanoma