PXD058823 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | ¬An Aurora kinase A-BOD1L1-PP2A B56 Axis promotes chromosome segregation fidelity |
Description | The goal of this experiment was to discover mediators of resistance to the MCAK agonist chemical UMK57. Naive SW620 cells were compared to cells exposed to UMK57 for 3 days, and then all cells were synchronized in mitosis. The cells were then harvested, frozen and sent for phosphoproteomic analysis. 3 independent biological repeats were performed over 3 consecutive weeks. |
HostingRepository | PRIDE |
AnnounceDate | 2025-02-18 |
AnnouncementXML | Submission_2025-02-18_10:32:04.463.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Thomas Kucharski |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | phosphorylated residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-12-12 11:48:44 | ID requested | |
⏵ 1 | 2025-02-18 10:32:04 | announced | |
Publication List
Keyword List
submitter keyword: aurora kinase,kinase, phosphoproteome, phosphatase |
Contact List
Duane Compton |
contact affiliation | Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth |
contact email | Duane.A.Compton@dartmouth.edu |
lab head | |
Thomas Kucharski |
contact affiliation | McGill University |
contact email | thomas.kucharski@mail.mcgill.ca |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD058823 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD058823
- Label: PRIDE project
- Name: ¬An Aurora kinase A-BOD1L1-PP2A B56 Axis promotes chromosome segregation fidelity