PXD058821

PXD058821 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	¬An Aurora kinase A-BOD1L1-PP2A B56 Axis promotes chromosome segregation fidelity
Description	The objective of this experiment is to discover mediators of resistance to the MCAK agonist compound UMK57. In this experiment, SW620 cells treated with DMSO were compared to SW620 cells exposed to UMK57 for 3 days prior to mitotic synchronization and harvesting. The samples were then processed and analyzed for differences in total protein levels. The experiment was performed as 3 independent biological repeats on 3 consective weeks.
HostingRepository	PRIDE
AnnounceDate	2025-02-18
AnnouncementXML	Submission_2025-02-18_10:31:39.801.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Thomas Kucharski
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-12 11:11:50	ID requested
⏵ 1	2025-02-18 10:31:40	announced

Publication List

10.1016/J.CELREP.2025.115317;

10.1016/J.CELREP.2025.115317;

Keyword List

submitter keyword: kinase, phosphatase, kinetochore, Aurora A

submitter keyword: kinase, phosphatase, kinetochore, Aurora A

Contact List

Duane Compton
contact affiliation	Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth
contact email	Duane.A.Compton@dartmouth.edu
lab head
Thomas Kucharski
contact affiliation	McGill University
contact email	thomas.kucharski@mail.mcgill.ca
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD058821
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD058821

PRIDE project URI

Repository Record List

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