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PXD058807

PXD058807 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleEarly innate immune response and evolution of a SARS-CoV-2 furin cleavage site inactive variant in bat cells
DescriptionSARS-CoV-2 has caused the largest known coronavirus pandemic and is believed to have emerged from insectivorous bats. Little is known about the evolution of these viruses in their reservoir bat species. In this study, we investigated SARS-CoV-2-host interaction using human and bat cells. Bat cells mount a robust and early antiviral response but elicit a dampened pro-inflammatory response upon SARS-CoV-2 infection compared to human cells.
HostingRepositoryPRIDE
AnnounceDate2025-06-05
AnnouncementXMLSubmission_2025-06-05_09:15:00.552.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYoan Machado
SpeciesList scientific name: Eptesicus fuscus; NCBI TaxID: 29078; scientific name: Homo sapiens (Human); NCBI TaxID: 9606; scientific name: Severe acute respiratory syndrome coronavirus 2; NCBI TaxID: 2697049;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentmaXis
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-12-12 02:23:03ID requested
12025-06-05 09:15:00announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: SARS-Cov-2, QTOF, human, interferon, immunity, bats
Contact List
Arinjay Banerjee
contact affiliation1- Vaccine and Infectious Disease Organization (VIDO), University of Saskatchewan, Saskatoon, SK, Canada
contact emailarinjay.banerjee@usask.ca
lab head
Yoan Machado
contact affiliationAmgen. Inc
contact emailymachado@amgen.com
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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