PXD058807 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Early innate immune response and evolution of a SARS-CoV-2 furin cleavage site inactive variant in bat cells |
Description | SARS-CoV-2 has caused the largest known coronavirus pandemic and is believed to have emerged from insectivorous bats. Little is known about the evolution of these viruses in their reservoir bat species. In this study, we investigated SARS-CoV-2-host interaction using human and bat cells. Bat cells mount a robust and early antiviral response but elicit a dampened pro-inflammatory response upon SARS-CoV-2 infection compared to human cells. |
HostingRepository | PRIDE |
AnnounceDate | 2025-06-05 |
AnnouncementXML | Submission_2025-06-05_09:15:00.552.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yoan Machado |
SpeciesList | scientific name: Eptesicus fuscus; NCBI TaxID: 29078; scientific name: Homo sapiens (Human); NCBI TaxID: 9606; scientific name: Severe acute respiratory syndrome coronavirus 2; NCBI TaxID: 2697049; |
ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | maXis |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-12-12 02:23:03 | ID requested | |
⏵ 1 | 2025-06-05 09:15:00 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: SARS-Cov-2, QTOF, human, interferon, immunity, bats |
Contact List
Arinjay Banerjee |
contact affiliation | 1- Vaccine and Infectious Disease Organization (VIDO), University of Saskatchewan, Saskatoon, SK, Canada |
contact email | arinjay.banerjee@usask.ca |
lab head | |
Yoan Machado |
contact affiliation | Amgen. Inc |
contact email | ymachado@amgen.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD058807 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD058807
- Label: PRIDE project
- Name: Early innate immune response and evolution of a SARS-CoV-2 furin cleavage site inactive variant in bat cells