PXD058807

PXD058807 is an original dataset announced via ProteomeXchange.

Title	Early innate immune response and evolution of a SARS-CoV-2 furin cleavage site inactive variant in bat cells
Description	SARS-CoV-2 has caused the largest known coronavirus pandemic and is believed to have emerged from insectivorous bats. Little is known about the evolution of these viruses in their reservoir bat species. In this study, we investigated SARS-CoV-2-host interaction using human and bat cells. Bat cells mount a robust and early antiviral response but elicit a dampened pro-inflammatory response upon SARS-CoV-2 infection compared to human cells.
HostingRepository	PRIDE
AnnounceDate	2025-06-05
AnnouncementXML	Submission_2025-06-05_09:15:00.552.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yoan Machado
SpeciesList	scientific name: Eptesicus fuscus; NCBI TaxID: 29078; scientific name: Homo sapiens (Human); NCBI TaxID: 9606; scientific name: Severe acute respiratory syndrome coronavirus 2; NCBI TaxID: 2697049;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	maXis

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-12 02:23:03	ID requested
⏵ 1	2025-06-05 09:15:00	announced

Dataset with its publication pending

submitter keyword: SARS-Cov-2, QTOF, human, interferon, immunity, bats

Arinjay Banerjee
contact affiliation	1- Vaccine and Infectious Disease Organization (VIDO), University of Saskatchewan, Saskatoon, SK, Canada
contact email	arinjay.banerjee@usask.ca
lab head
Yoan Machado
contact affiliation	Amgen. Inc
contact email	ymachado@amgen.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD058807

PRIDE project URI

• PRIDE
  1. PXD058807
     1. Label: PRIDE project
     2. Name: Early innate immune response and evolution of a SARS-CoV-2 furin cleavage site inactive variant in bat cells