PXD058789

PXD058789 is an original dataset announced via ProteomeXchange.

Title	BACE2 and lipid metabolism (DMSO versus BACE2i 3I proteomic analysis)
Description	proteomic analysis of melanoma, PDAC cells and fibroblast treated with DMSO vs 3I
HostingRepository	PRIDE
AnnounceDate	2026-02-09
AnnouncementXML	Submission_2026-02-08_21:30:32.999.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	vittoria matafora
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF; Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-11 15:04:30	ID requested
⏵ 1	2026-02-08 21:30:33	announced

10.1186/s13046-025-03626-x;

Matafora V, Elhagh A, Morelli A, Tronci L, Cattaneo A, Conti C, Casagrande F, Farris F, Bachi A, BACE2 tunes lipid uptake through lipid transporters shedding supporting cancer cell proliferation. J Exp Clin Cancer Res, 45(1):36(2026) [pubmed]

submitter keyword: BACE2 lipid metabolism

Angela Bachi
contact affiliation	IFOM
contact email	angela.bachi@ifom.eu
lab head
vittoria matafora
contact affiliation	ifom
contact email	vittoria.matafora@ifom.eu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/02/PXD058789

PRIDE project URI

• PRIDE
  1. PXD058789
     1. Label: PRIDE project
     2. Name: BACE2 and lipid metabolism (DMSO versus BACE2i 3I proteomic analysis)