PXD058708

PXD058708 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	DIA quantitative protein mass spectrometry of RBE cells knockout NAT10
Description	To further explore the role of NAT10 in ICC, we constructed stable NAT10-knockdown RBE cells using shRNA and performed DIA quantitative proteomic analysis to explore its influence on downstream protein fuction.
HostingRepository	PRIDE
AnnounceDate	2026-05-25
AnnouncementXML	Submission_2026-05-24_17:23:23.179.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kainan Lin
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Astral

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-09 16:45:12	ID requested
⏵ 1	2026-05-24 17:23:23	announced

Publication List

10.1073/pnas.2532263123;
Lu Y, Lin K, Wang Q, Huang X, Lin L, Dou J, Jiao Y, Wang Y, Xiao P, Chen H, Li S, Xue Y, He S, Xu J, C drives intrahepatic cholangiocarcinoma by suppressing transposable elements via chromatin remodeling. Proc Natl Acad Sci U S A, 123(20):e2532263123(2026) [pubmed]

10.1073/pnas.2532263123;

Lu Y, Lin K, Wang Q, Huang X, Lin L, Dou J, Jiao Y, Wang Y, Xiao P, Chen H, Li S, Xue Y, He S, Xu J, C drives intrahepatic cholangiocarcinoma by suppressing transposable elements via chromatin remodeling. Proc Natl Acad Sci U S A, 123(20):e2532263123(2026) [pubmed]

Keyword List

submitter keyword: Intrahepatic cholangiocarcinoma;NAT10;DIA

submitter keyword: Intrahepatic cholangiocarcinoma;NAT10;DIA

Contact List

Junjie Xu
contact affiliation	Run Run Shaw Hospital, Zhejiang University School of Medicine
contact email	walter235@126.com
lab head
Kainan Lin
contact affiliation	Run Run Shaw Hospital, Zhejiang University School of Medicine
contact email	lkn645916473@163.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/05/PXD058708
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/05/PXD058708

PRIDE project URI

Repository Record List

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