PXD058707

PXD058707 is an original dataset announced via ProteomeXchange.

Title	Extrinsic and Intrinsic Factors Affect Copper-Induced Protein Precipitation Across Eukaryotic and Prokaryotic Proteomes
Description	The susceptibility of a protein to aggregation upon exposure to copper ions (Cu) has been recognized as a contributor to Cu-induced cellular dysfunction and toxicity. Different cell types succumb to Cu to varying degrees, indicating innate differences between species in the mechanisms used to tolerate exposure to Cu in excess of their biological needs. Investigated here are properties associated with metal-induced protein precipitation (MiPP) compared across cell lysates generated from three cell lines from three different species: Escherichia coli, Candida albicans, and the human prostate cancer cell line 22Rv1.
HostingRepository	PRIDE
AnnounceDate	2025-05-15
AnnouncementXML	Submission_2025-05-15_06:54:40.760.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	grace bertles
SpeciesList	scientific name: Candida albicans (Yeast); NCBI TaxID: 5476; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-09 16:13:58	ID requested
⏵ 1	2025-05-15 06:54:41	announced

10.1002/PRO.70158;

submitter keyword: Copper,Proteomics, candida albicans, protein precipitation, metal

Michael Fitzgerald
contact affiliation	Chemistry, Duke University
contact email	michael.c.fitzgerald@duke.edu
lab head
grace bertles
contact affiliation	Duke University
contact email	grace.bertles@duke.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD058707

PRIDE project URI

• PRIDE
  1. PXD058707
     1. Label: PRIDE project
     2. Name: Extrinsic and Intrinsic Factors Affect Copper-Induced Protein Precipitation Across Eukaryotic and Prokaryotic Proteomes