PXD058691

PXD058691 is an original dataset announced via ProteomeXchange.

Title	To investigate how Trametinib affects colorectal CAFs in ECM production and remodeling
Description	Data independent acquisition (DIA) mass spectrometry was used to study the role of the MEK1/2 inhibitor Trametinib on the ability of colorectal CAFs to produce and modify the extracellular matrix
HostingRepository	PRIDE
AnnounceDate	2026-02-12
AnnouncementXML	Submission_2026-02-11_23:54:50.337.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ujjwal Suwal
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-09 03:27:53	ID requested
⏵ 1	2026-02-11 23:54:50	announced

Dataset with its publication pending

submitter keyword: CAFs, Trametinib, DIA mass spectrometry, FAIMS-Orbitrap Lumos

Jyrki Heino
contact affiliation	Department of Life Technologies, InFLAMES Flagship, University of Turku, 20520 Turku, Finland
contact email	jyrki.heino@utu.fi
lab head
Ujjwal Suwal
contact affiliation	University of Turku
contact email	ujjwal.suwal@utu.fi
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/02/PXD058691

PRIDE project URI

• PRIDE
  1. PXD058691
     1. Label: PRIDE project
     2. Name: To investigate how Trametinib affects colorectal CAFs in ECM production and remodeling