PXD058680
PXD058680 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | AKR1B10 inhibition enhances c-Myc stability by disrupting PP2A assembly |
| Description | Immunoprecipitation-MS analysis to identify AKR1B10 interacting proteins. |
| HostingRepository | iProX |
| AnnounceDate | 2025-06-26 |
| AnnouncementXML | Submission_2025-09-11_20:12:11.625.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Xiaoxue Wu |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-12-08 20:03:49 | ID requested | |
| 1 | 2025-06-25 22:15:38 | announced | |
| ⏵ 2 | 2025-09-11 20:12:12 | announced | 2025-09-12: Add info. |
Publication List
| Wu X, Huang S, Gao J, Huang S, Chen L, Zhao Z, Pu R, Ma X, Liu X, He W, Song M, AKR1B10 dictates c-Myc stability to suppress colorectal cancer metastasis via PP2A nitration. Sci Adv, 11(34):eadv6937(2025) [pubmed] |
Keyword List
| submitter keyword: AKR1B10, colorectal cancer, metastasis, PP2A, c-Myc |
Contact List
| Mei Song | |
|---|---|
| contact affiliation | Institute of Precision Medicine, The First Affiliated Hospital of Sun Yat-Sen University, Sun Yat-Sen University |
| contact email | songm7@mail.sysu.edu.cn |
| lab head | |
| Xiaoxue Wu | |
| contact affiliation | Institute of Precision Medicine, The First Affiliated Hospital of Sun Yat-Sen University, Sun Yat-Sen University |
| contact email | 386060402@qq.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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