PXD058612

PXD058612 is an original dataset announced via ProteomeXchange.

Title	High-resolution analyses of the secretomes from primary human skeletal muscle cells
Description	Myokines released by skeletal muscle in response to contraction may contribute to the health-promoting effects of exercise. Previous studies with cultured rodent and human myotubes have revealed highly complex patterns of myokine secretion. However, the commonalities and differences in the secretory response of the different cell models have not been explored, limiting the interpretation of these results. In the present study, we performed a comprehensive analysis of contraction-regulated secretomes using the most commonly used skeletal muscle cell models.
HostingRepository	PRIDE
AnnounceDate	2025-04-11
AnnouncementXML	Submission_2025-04-11_08:20:11.220.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Michael Turewicz
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos; Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-05 07:53:11	ID requested
⏵ 1	2025-04-11 08:20:11	announced

10.3389/FPHYS.2025.1549316;

submitter keyword: secretomes, myokines, muscle contraction, mass spectrometry, EPS,HSkMCs

Hadi Al-Hasani
contact affiliation	Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center (DDZ), Leibniz Center for Diabetes Research at Heinrich-Heine-University Düsseldorf, Auf´m Hennekamp 65, 40225 Düsseldorf, Germany
contact email	Hadi.Al-Hasani@ddz.de
lab head
Michael Turewicz
contact affiliation	Institute for Clinical Biochemistry and Pathobiochemistry German Diabetes Center (DDZ) Leibniz Center for Diabetes Research at Heinrich-Heine-University Düsseldorf Auf´m Hennekamp 65 40225 Düsseldorf Germany
contact email	michael.turewicz@ddz.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/04/PXD058612

PRIDE project URI

• PRIDE
  1. PXD058612
     1. Label: PRIDE project
     2. Name: High-resolution analyses of the secretomes from primary human skeletal muscle cells