PXD058589 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Rat Optic Nerve Head Extracellular vesicle analysis |
| Description | The optic nerve head in young adult rodents contains 10 different cell types, each which secretes extracellular vesicles. We isolated rat optic nerve heads aand dissociated them in cell culture, in triplicate, from n=20 rat optic nerve heads/culture and collected and purified the extracellular vesicles (EVs)from the conditioned medium of the first 3 platings of the primary cell cultures. We performed proteomic analysis of the EVs using a variety of techniques EVs were then analyzed by both western analysis and HPLC-tandem MS/MS analysis, and proteomic analysis performed and peptides compared against a human protein database. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-04-15 |
| AnnouncementXML | Submission_2026-04-15_11:56:27.993.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Steven Bernstein |
| SpeciesList | scientific name: Rattus norvegicus (Rat); NCBI TaxID: NEWT:10116; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2024-12-04 16:08:59 | ID requested | |
| ⏵ 1 | 2026-04-15 11:56:28 | announced | |
Publication List
Keyword List
Contact List
| Steven L. |
|---|
| contact affiliation | Department of Ophthalmology and Visual Sciences University of Maryland at Baltimore School of Medicine |
| contact email | sbernstein@som.umaryland.edu |
| lab head | |
| Steven Bernstein |
|---|
| contact affiliation | University of Maryland-Baltimore School of Medicine |
| contact email | sbernstein@som.umaryland.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD058589 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD058589
- Label: PRIDE project
- Name: Rat Optic Nerve Head Extracellular vesicle analysis
