PXD058554

PXD058554 is an original dataset announced via ProteomeXchange.

Title	Proteomic profiling of serum-derived extracellular vesicles in diffuse idiopathic skeletal hyperostosis patients
Description	This study aims to investigate the protein contents of serum-EVs associated with diffuse idiopathic skeletal hyperostosis (DISH) and identify the potential biomarkers for the diagnosis of DISH. Serum-EVs were separated using differential centrifugation technique. Label-free-liquid chromatography mass spectrometry (LC-MS/MS) was utilized to identify differentially expressed proteins (DEPs) highly associated with DISH. DEPs’ expression levels were tested using Enzyme-linked immunosorbent assay (ELISA) and bioinformatic analyses were performed.
HostingRepository	iProX
AnnounceDate	2024-12-03
AnnouncementXML	Submission_2024-12-03_22:37:20.455.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Haicheng Zhou
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-03 22:30:55	ID requested
⏵ 1	2024-12-03 22:37:20	announced

Dataset with its publication pending

submitter keyword: diffuse idiopathic skeletal hyperostosis, serum, extracellular vesicles, proteomic analysis

Hongpan Xu
contact affiliation	Nanjing Drum Tower Hospital, Affiliated Hospital of Medical, Nanjing University
contact email	1073464742@qq.com
lab head
Haicheng Zhou
contact affiliation	Nanjing Drum Tower Hospital, Affiliated Hospital of Medical, Nanjing University
contact email	zhouhcnju@163.com
dataset submitter

iProX dataset URI