PXD058527

PXD058527 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	SSR4 deficiency in B-cell reshapes the inflammatory microenvironment
Description	The development and differentiation of infiltrating B cells influence the structure of the immune microenvironment (TIME). We aimed to unveil the impact of regulating B cell development and antibodies secretion by glycosylation modification-associated protein SSR4 on the formation of IME structures and anti-tumor immunity in colorectal cancer (CRC)
HostingRepository	PRIDE
AnnounceDate	2026-09-07
AnnouncementXML	Submission_2026-09-06_16:34:20.863.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	薇赵
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Elite

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-03 05:06:48	ID requested
⏵ 1	2026-09-06 16:34:21	announced

Publication List

10.1002/advs.75790;
Zhao W, Zhao Y, Li H, Yang B, Lu S, Fu X, Zhang C, Chen Y, Bian X, Ma X, Yang X, Wang B, Fang Y, Yang L, Zhao Y, Zhao S, SSR4 Sustains Tertiary Lymphoid Structures by Regulation Quality Control of N-linked Glycosylation During B-cell Differentiation Into Plasmacyte in Colorectal Cancer. Adv Sci (Weinh), 13(46):e75790(2026) [pubmed]

10.1002/advs.75790;

Zhao W, Zhao Y, Li H, Yang B, Lu S, Fu X, Zhang C, Chen Y, Bian X, Ma X, Yang X, Wang B, Fang Y, Yang L, Zhao Y, Zhao S, SSR4 Sustains Tertiary Lymphoid Structures by Regulation Quality Control of N-linked Glycosylation During B-cell Differentiation Into Plasmacyte in Colorectal Cancer. Adv Sci (Weinh), 13(46):e75790(2026) [pubmed]

Keyword List

submitter keyword: Mouse，B cells,SSR4 deficiency

submitter keyword: Mouse，B cells,SSR4 deficiency

Contact List

Shuli Zhao
contact affiliation	Nanjing First Hospital
contact email	shulizhao79@njmu.edu.cn
lab head
薇赵
contact affiliation	Nanjing First Hospital
contact email	zhaowei_njmu@163.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD058527
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD058527

PRIDE project URI

Repository Record List

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