⮝ Full datasets listing
PXD058371
PXD058371 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Ascorbate prevents spontaneous liver tumor development in mice with double deficiency of superoxide dismutase 1 and peroxiredoxin 4 |
| Description | NASH developed in Sod1- and Prdx4-double KO mice progressed to hepatic tumors. Supplementation of ascorbate (Asc) effectively suppressed the tumor development. Upregulated amino acid metabolisms in precancerous cells likely supports tumorigenic growth. Asc appears to induce ferroptosis in cells destined for tumorigenic transformation. |
| HostingRepository | jPOST |
| AnnounceDate | 2025-11-28 |
| AnnouncementXML | Submission_2025-11-27_07:00:05.411.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Tsukasa Osaki |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
| ModificationList | S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-11-28 02:13:49 | ID requested | |
| ⏵ 1 | 2025-11-27 07:00:05 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: mouse liver |
Contact List
| Tsukasa Osaki | |
|---|---|
| lab head | |
| Tsukasa Osaki | |
| contact affiliation | Yamagata University |
| dataset submitter | |
Full Dataset Link List
| jPOST dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003491/ |
