⮝ Full datasets listing
PXD058250
PXD058250 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | NEOPALANA Proteomgenomic analysis |
| Description | Neoadjuvant palbociclib and anastrozole (NeoPalAna) is a single-arm phase II clinical trial for patients with stage II/III ER+/HER2- breast cancer. Patients recieved Anastrozole for 4weeks followed by palbociclib. On day 15, patients were biopsied and Ki67% was determined. Patients with Ki67 >10% were deemed resistant to therapy. These biopsies were subsequently frozen for multi-omics processing |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-02-09 |
| AnnouncementXML | Submission_2026-02-08_16:10:36.321.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Matthew Holt |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-11-25 12:53:53 | ID requested | |
| ⏵ 1 | 2026-02-08 16:10:37 | announced |
Publication List
| 10.1038/s41467-026-68570-6; |
| Kong T, Mabry A, Highkin M, Wang AZ, Hoog J, Guo Z, Gonzales-Gonzales A, Thomas S, Song Y, Gao F, Opyrchal M, Peterson L, Ademuyiwa F, Margenthaler J, Aft R, Glover-Collins K, Nehring L, Tao Y, Sanati S, Hagemann IS, Boulos F, Holt M, Ding L, Zhu W, Oh ST, Wang J, Witkiewicz AK, Knudsen ES, Bose R, Weber JD, Goetz M, Northfelt D, Luo J, Ma CX, Biomarkers of response to neoadjuvant palbociclib plus anastrozole in endocrine-resistant estrogen receptor-positive/HER2-negative breast cancer: a phase 2 trial. Nat Commun, 17(1):949(2026) [pubmed] |
Keyword List
| submitter keyword: Estrogen Receptor, Endocrine therapy,Breast Cancer |
Contact List
| Matthew V Holt | |
|---|---|
| contact affiliation | Baylor College of Medicine |
| contact email | mvholt@bcm.edu |
| lab head | |
| Matthew Holt | |
| contact affiliation | BCM |
| contact email | mvholt@bcm.edu |
| dataset submitter | |
Full Dataset Link List
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/02/PXD058250 |
| PRIDE project URI |
Repository Record List
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