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PXD058230

PXD058230 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleBeclin 1 of megakaryocytic lineage cells is locally dispensable for platelet hemostasis but functions distally in bone homeostasis
DescriptionBecn1 deficiency in the megakaryocytic lineage reduces sex hormone-binding globulin (SHBG), thus releasing testosterone into the blood and ultimately leading to increased bone mass and improved bone quality.
HostingRepositoryPRIDE
AnnounceDate2025-05-07
AnnouncementXMLSubmission_2025-05-07_04:59:44.807.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterZhao Chen
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-11-25 06:11:15ID requested
12025-05-07 04:59:45announced
Publication List
10.1038/s41413-025-00410-7;
Li L, Zhao C, Zhang R, Wei W, Liu B, Dong J, Gao X, Zhang D, Wang X, Lu M, Zhang Y, Yu Y, Yuan N, Xu Y, Wang J, Fang Y, Beclin 1 of megakaryocytic lineage cells is locally dispensable for platelet hemostasis but functions distally in bone homeostasis. Bone Res, 13(1):32(2025) [pubmed]
Keyword List
submitter keyword: Mouse, bone homeostasis,Beclin1
Contact List
Wang Jianrong
contact affiliationSoochow University
contact emailjrwang@suda.edu.cn
lab head
Zhao Chen
contact affiliationSoochow University
contact emailczhao7@stu.suda.edu.cn
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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