PXD058131 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomics and metabolomics of different delivery modes in human pregnancy |
Description | This project investigates the impact of different delivery modes and labor on maternal and neonatal health by analyzing 40 participants, including 16 spontaneous vaginal deliveries (VD), 16 prelabor cesarean deliveries (CS), and 8 intrapartum cesarean sections (Intra_CS). Using label-free proteomics and untargeted metabolomics, both amniotic fluid and cord blood samples were analyzed respectively to identify variations in protein and metabolite profiles associated with the mode of delivery. The study aims to uncover biological pathways influenced by labor and delivery mode, providing insights into how these factors shape maternal and neonatal outcomes, with implications for improving perinatal care and long-term health strategies. |
HostingRepository | PRIDE |
AnnounceDate | 2025-05-07 |
AnnouncementXML | Submission_2025-05-07_05:36:23.511.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yun Huang |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Exploris 480 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-11-21 04:18:45 | ID requested | |
⏵ 1 | 2025-05-07 05:36:24 | announced | |
Publication List
Huang Y, Ni Y, Meng Y, Zeng X, He X, Zhang L, Zhang J, Integrated proteomics and metabolomics network analysis across different delivery modes in human pregnancy: a pilot study. BMC Pregnancy Childbirth, 24(1):868(2024) [pubmed] |
10.1186/s12884-024-07097-4; |
Keyword List
submitter keyword: Proteomics |
metabolomics |
delivery modes |
Contact List
Yun Huang |
contact affiliation | Jun Jim Zhangjunjimzhang@sjtu.edu.cnMinistry of Education-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine |
contact email | yunhuang.pku@gmail.com |
lab head | |
Yun Huang |
contact affiliation | Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine |
contact email | yunhuang.pku@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD058131
- Label: PRIDE project
- Name: Proteomics and metabolomics of different delivery modes in human pregnancy