⮝ Full datasets listing
PXD058114
PXD058114 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | DDX1-Mediated mitochondrial DNA G-quadruplex Resolution Is Essential for Hematopoietic Stem Cell Homeostasis and Radioresistance |
| Description | Sorted CD34+ hematopoietic stem cells (HSCs) were cultured overnight at 37°C in a humidified incubator with 5% CO₂. The cells were then exposed to 5 Gy X-ray irradiation and cultured for an additional 24 hours. For each experimental condition (irradiated and non-irradiated), 1*10^7 CD34+ HSCs were collected. Mitochondrial proteins were extracted using the Mitochondrial Protein Extraction Kit (Beyotime, Cat. No. C3601). Subsequent LC-MS/MS analysis, sequence database searching, and bioinformatics analyses were conducted by Bioprofile Co., Ltd. |
| HostingRepository | iProX |
| AnnounceDate | 2024-11-21 |
| AnnouncementXML | Submission_2025-12-30_23:55:56.194.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jiankun Fan |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Astral |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-11-20 21:23:49 | ID requested | |
| ⏵ 1 | 2025-12-30 23:55:56 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: CD34+HSC, mitochondria, Mitochondrial Proteomics, radiation |
Contact List
| jiankun Fan | |
|---|---|
| contact affiliation | School of Basic Medical Sciences, Chongqing Medical University |
| contact email | 591314882@qq.com |
| lab head | |
| Jiankun Fan | |
| contact affiliation | School of Basic Medical Sciences, Chongqing Medical University |
| contact email | 591314882@QQ.COM |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
