PXD058113
PXD058113 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic analysis of rG4_A selectively degraded proteins through the proteasome |
| Description | To explore the effects of rG4-PROTACs on the whole proteome, Hela cells were treated with blank (empty transfection control), rG4 mut_A, rG4_A, or rG4_A plus MG132, and a proteomic analysis was included in the subproject |
| HostingRepository | iProX |
| AnnounceDate | 2024-11-21 |
| AnnouncementXML | Submission_2025-08-20_19:11:53.332.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Kun Zhang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-11-20 21:22:05 | ID requested | |
| 1 | 2024-11-20 21:22:27 | announced | |
| ⏵ 2 | 2025-08-20 19:11:54 | announced | 2025-08-21: Add info. |
Publication List
| Zhang K, Nie Q, Li M, Chen X, Zhong L, Dai T, Guo X, Zhao H, Lau TC, Wang H, Chen SB, Kwok CK, RNA G-quadruplex structure-based PROTACs for targeted DHX36 protein degradation and gene activity modulation in mammalian cells. Nucleic Acids Res, 53(3):(2025) [pubmed] |
Keyword List
| submitter keyword: RNA, RNA binding proteins, protein degradation |
Contact List
| Chunkit Kwok | |
|---|---|
| contact affiliation | City University of Hong Kong |
| contact email | ckkwok42@cityu.edu.hk |
| lab head | |
| Kun Zhang | |
| contact affiliation | City University of Hong Kong |
| contact email | kuzhang@cityu.edu.hk |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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