PXD058111
PXD058111 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Molecular insights into oocyte development and sperm storage in black rockfish (Sebastes schlegelii): proteomic changes across reproductive stages |
| Description | This study investigated the ovarian protein expression changes in black rockfish (Sebastes schlegelii) during key reproductive stages: pre-mating (PRM), POM, unmated control (POM-CT), and PRF. A total of 5,012 proteins were identified, with notable fluctuations in protein expression observed at the PRF stage. Specifically, 140 proteins were upregulated and 615 downregulated when compared to the PRM stage, while 101 proteins were upregulated and 531 downregulated in comparison to the POM stage. The functional enrichment analysis of differentially expressed proteins (DEPs) revealed distinct pathways: POM vs. PRM showed involvement in vesicle sorting and hormone signaling; PRF vs. POM indicated pathways related to chromatin remodeling and gene expression regulation; and POM vs. POM-CT highlighted pathways associated with immune response. These findings suggested that these signaling pathways may play a crucial role in oocyte development and sperm storage. The majority of DEPs were localized in the nucleus, with key interactions involving proteins such as GSK3B and MED1. These findings enhance our understanding of the molecular mechanisms underlying oocyte maturation and sperm storage, providing insights relevant to reproductive biology and aquaculture practices. |
| HostingRepository | iProX |
| AnnounceDate | 2024-11-21 |
| AnnouncementXML | Submission_2024-11-20_21:05:56.567.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Ying Chen |
| SpeciesList | scientific name: Sebastes schlegelii; NCBI TaxID: 214486; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-11-20 21:05:35 | ID requested | |
| ⏵ 1 | 2024-11-20 21:05:56 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: black rockfish ovary LC-MSMS |
Contact List
| Jie Qi | |
|---|---|
| contact affiliation | Ocean University of China |
| contact email | qijie@ouc.edu.cn |
| lab head | |
| Ying Chen | |
| contact affiliation | Ocean University of China |
| contact email | 15092067730@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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