PXD057977

PXD057977 is an original dataset announced via ProteomeXchange.

Title	OLFM4 is a direct target of the cGAS-STING pathway and acts as an extracellular inhibitor for the Hippo signaling in EBV-associated cancer
Description	To investigate protein components of MVs in EBVaGC, we collected clinical tissue samples of 3 EBV+ and 3 EBV- gastric cancer patients, and isolated MVs from these samples. Then performed 4D-label free quantitative proteomics analysis for each isolated MVs. Raw files of 6 samples are included in subproject.
HostingRepository	iProX
AnnounceDate	2024-11-18
AnnouncementXML	Submission_2024-12-15_22:55:47.397.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Fuping Wen
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-17 22:01:29	ID requested
1	2024-11-17 22:01:53	announced
⏵ 2	2024-12-15 22:55:48	announced	2024-12-16: Add Publication.

Wen F, Han Y, Zhang H, Zhao Z, Wang W, Chen F, Qin W, Ju J, An L, Meng Y, Yang J, Tang Y, Zhao Y, Zhang H, Li F, Bai W, Xu Y, Zhou Z, Jiao S, Epstein-Barr virus infection upregulates extracellular OLFM4 to activate YAP signaling during gastric cancer progression. Nat Commun, 15(1):10543(2024) [pubmed]

submitter keyword: Epstein-Barr virus, Gastric cancer, Hippo pathway, Microvesicles, OLFM4

Zhaocai Zhou
contact affiliation	Fudan University
contact email	zhouzhaocai@fudan.edu.cn
lab head
Fuping Wen
contact affiliation	Shanghai Tenth People's Hospital
contact email	pings2008@163.com
dataset submitter

iProX dataset URI