PXD057976
PXD057976 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Optimizing the structural features of the dioxygenated benzo lead compound |
| Description | We proposed a rational design of spatial configurations to develop dioxygenated derivatives that adhere to specific conformational requirements. This strategy is anticipated to enhance the spatial binding affinity of the inhibitors with FabH, aiming to improve binding affinity while concurrently minimizing off-target effects, thereby further augmenting antibacterial efficacy. |
| HostingRepository | iProX |
| AnnounceDate | 2024-11-18 |
| AnnouncementXML | Submission_2024-11-17_21:53:11.137.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Rui Wang |
| SpeciesList | scientific name: Escherichia coli; NCBI TaxID: 562; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-11-17 21:52:48 | ID requested | |
| ⏵ 1 | 2024-11-17 21:53:11 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: FabH, LipMS |
Contact List
| Rui Wang | |
|---|---|
| contact affiliation | Shenzhen Bay Laboratory |
| contact email | wangrui2011pku@gmail.com |
| lab head | |
| Rui Wang | |
| contact affiliation | Shenzhen Bay Laboratory |
| contact email | wangrui@szbl.ac.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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