PXD057817
PXD057817 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic analysis of meninges from autoimmune encephalitis (mouse model) |
| Description | We developed a B-cell-mediated mouse model of Anti-N-Methyl-D-aspartate receptor autoimmune encephalitis (AE) by immunization with a GluN1359–378 peptide. In our model, mice display a series of symptoms that recapitulate autoimmune encephalitis such as anxiety behaviour and spatial memory impairment (Wagnon et al, Brain 2020) . Proteomic analysis of AE meninges showed enrichment of differentially expressed proteins in biological processes associated with B cell activation and cytokine signalling pathways. |
| HostingRepository | iProX |
| AnnounceDate | 2024-11-12 |
| AnnouncementXML | Submission_2024-11-12_20:01:55.231.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Benoit Bernay |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-11-12 20:01:35 | ID requested | |
| ⏵ 1 | 2024-11-12 20:01:55 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Autoimmune encephalitis, meninges, T cells, B cells, proteomic analysis |
Contact List
| Olivier Toutirais | |
|---|---|
| contact affiliation | US EMerode, Plateforme Proteogen, Université de Caen, France |
| contact email | toutirais-o@chu-caen.fr |
| lab head | |
| Benoit Bernay | |
| contact affiliation | US EMerode, Plateforme Proteogen, Université de Caen, France |
| contact email | benoit.bernay@unicaen.fr |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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