PXD057741
PXD057741 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Nuclear VCP-like 2 (NVL2)-associated complex |
Description | LC-MSMS analysis of NVL2-associated pre-60S complex. To obtain more insights into the molecular mechanism of this effects caused by the mutant NVL2 in pre-60S complexes,we searched for additional proteins that preferentially interact with the NVL2(E365Q/E682Q) in comparison with wild-type NVL2. Co-mmunoprecipitation was performed by using FLAG-tagged NVL2 (wild-type or E365Q/E682Q) as baits and their interacting proteins were analyzed by LC-MS/MS. |
HostingRepository | jPOST |
AnnounceDate | 2025-01-31 |
AnnouncementXML | Submission_2025-01-30_07:00:11.462.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Keiichi Izumikawa |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | S-carboxamidomethyl-L-cysteine; alpha-amino acetylated residue; 2-pyrrolidone-5-carboxylic acid (Gln); L-methionine sulfoxide |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2024-11-11 04:33:20 | ID requested | |
⏵ 1 | 2025-01-30 07:00:12 | announced |
Publication List
Hirooka Y, Izumikawa K, Miyao S, Ohga T, Nobe Y, Taoka M, Nagahama M, Pre-ribosomal WDR74 module coordinates the early and late pre-rRNA processing stages for the NVL2-mediated regulation of 60S ribosome biogenesis. Biochem Biophys Res Commun, 744():151175(2025) [pubmed] |
Keyword List
submitter keyword: NVL2 |
Contact List
Masami Nagahama | |
---|---|
lab head | |
Keiichi Izumikawa | |
contact affiliation | Meiji pharmaceutical university |
dataset submitter |
Full Dataset Link List
jPOST dataset URI |
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003462/ |