⮝ Full datasets listing

PXD057712

PXD057712 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTenotomized Achilles tendons of MRL/MpJ mice show scar-mediated healing, but have superior recovery of biomechanical properties
DescriptionThe purpose of this project is to determine changes in proteins and signaling pathways in injured tendons of C57BL/6j and MRL/MpJ mice. The MRL.MpJ mice have been reported to have a strong repair ability compared to that of C57BL/6j mice. Identifying signaling pathways in MRL/MpJ tendons that are distinct from C57BL/6j tendons will help us understand the molecular mechanisms underlying the better healing ability of MRL/MpJ mice. The samples include normal and injured Achilles tendons 4 weeks after tenotomy surgery obtained from male and female C57BL/6j and MRL/MpJ. The Achilles injury surgery was performed at 12 weeks of age. Normal tendons were obtained age, sex and strain-matched mice without surgery. The collected normal and inured tendons were subjected to proteomics.
HostingRepositoryPRIDE
AnnounceDate2025-05-16
AnnouncementXMLSubmission_2025-05-16_07:44:56.023.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMehari Weldemariam
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-11-10 14:53:37ID requested
12025-05-16 07:44:56announced
Publication List
10.1101/2025.05.13.653102;
Keyword List
submitter keyword: Tendon C57BL/6j, injury, MRL/MpJ, Achilles tendon
Contact List
Maureen A.
contact affiliationUniversity of Maryland, School of Pharmacy, Department of Pharmaceutical Sciences, Baltimore, MD 21201
contact emailmkane@rx.umaryland.edu
lab head
Mehari Weldemariam
contact affiliationUniversity of Maryland Baltimore
contact emailmweldemariam@rx.umaryland.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD057712
PRIDE project URI
Repository Record List
[ + ]