PXD057712 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Tenotomized Achilles tendons of MRL/MpJ mice show scar-mediated healing, but have superior recovery of biomechanical properties |
Description | The purpose of this project is to determine changes in proteins and signaling pathways in injured tendons of C57BL/6j and MRL/MpJ mice. The MRL.MpJ mice have been reported to have a strong repair ability compared to that of C57BL/6j mice. Identifying signaling pathways in MRL/MpJ tendons that are distinct from C57BL/6j tendons will help us understand the molecular mechanisms underlying the better healing ability of MRL/MpJ mice. The samples include normal and injured Achilles tendons 4 weeks after tenotomy surgery obtained from male and female C57BL/6j and MRL/MpJ. The Achilles injury surgery was performed at 12 weeks of age. Normal tendons were obtained age, sex and strain-matched mice without surgery. The collected normal and inured tendons were subjected to proteomics. |
HostingRepository | PRIDE |
AnnounceDate | 2025-05-16 |
AnnouncementXML | Submission_2025-05-16_07:44:56.023.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Mehari Weldemariam |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-11-10 14:53:37 | ID requested | |
⏵ 1 | 2025-05-16 07:44:56 | announced | |
Publication List
Keyword List
submitter keyword: Tendon C57BL/6j, injury, MRL/MpJ, Achilles tendon |
Contact List
Maureen A. |
contact affiliation | University of Maryland, School of Pharmacy, Department of Pharmaceutical Sciences, Baltimore, MD 21201 |
contact email | mkane@rx.umaryland.edu |
lab head | |
Mehari Weldemariam |
contact affiliation | University of Maryland Baltimore |
contact email | mweldemariam@rx.umaryland.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD057712 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD057712
- Label: PRIDE project
- Name: Tenotomized Achilles tendons of MRL/MpJ mice show scar-mediated healing, but have superior recovery of biomechanical properties