PXD057702

PXD057702 is an original dataset announced via ProteomeXchange.

Title	Medium from human iPSC-derived primitive macrophages promote adult cardiomyocyte proliferation and cardiac regeneration
Description	human induced pluripotent stem cell (hiPSC)-derived primitive macrophages (hiPMs) and their conditioned medium (hiPM-CM) promote human cardiomyocyte proliferation and to enhance cardiac regeneration in infarcted adult mouse hearts. To identify the components underlying the pro-proliferative effects hiPM-CM, and the conditioned medium of hiPM precursors (hiPMpre-CM) were collected and the protein components were analyzed by mass spectrometry.
HostingRepository	PRIDE
AnnounceDate	2025-05-07
AnnouncementXML	Submission_2025-05-07_04:28:52.919.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	pengfei xu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-09 22:28:03	ID requested
⏵ 1	2025-05-07 04:28:53	announced

10.1038/s41467-025-58301-8;

Xiao Y, Zhang H, Liu X, Xu P, Du H, Wang J, Shen J, Li Y, Wang Y, He C, Feng H, Liu J, Zhou Y, Liu S, Gao Z, Zang J, Bi J, Tang TS, Gu Q, Wei T, Wang J, Song M, Medium from human iPSC-derived primitive macrophages promotes adult cardiomyocyte proliferation and cardiac regeneration. Nat Commun, 16(1):3012(2025) [pubmed]

submitter keyword: Human, macrophage, conditioned medium, LC-MS/MS

Moshi Song
contact affiliation	INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES
contact email	songmoshi@ioz.ac.cn
lab head
pengfei xu
contact affiliation	IOZ
contact email	xupengfei23@mails.ucas.ac.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD057702

PRIDE project URI

• PRIDE
  1. PXD057702
     1. Label: PRIDE project
     2. Name: Medium from human iPSC-derived primitive macrophages promote adult cardiomyocyte proliferation and cardiac regeneration