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PXD057649

PXD057649 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleGlial UDP-glycosyltransferase Ugt35b regulates longevity by maintaining lipid homeostasis in Drosophila
DescriptionTo validate the role of glial Ugt35b in lipid metabolism, we carried out co-immunoprecipitation experiments to identify physical interaction partners of Ugt35 in glial cells. For this, we expressed HA-tagged Ugt35b under the pan-glial driver (repo-GS) and fed the flies with RU486 for 10~14 days, followed by Orbitrap Astral mass spectrometry (MS) to identify co-immunoprecipitated proteins (IP-MS). Anti-HA beads were used for the experimental group, and anti-Flag beads were used for the control group .
HostingRepositoryiProX
AnnounceDate2024-12-03
AnnouncementXMLSubmission_2025-02-04_20:55:59.188.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterHong Li
SpeciesList scientific name: Drosophila melanogaster; NCBI TaxID: 7227;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Astral
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-11-07 23:43:37ID requested
⏵ 12025-02-04 20:55:59announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Glia, Ugt35b, Lipid droplets, Aging
Contact List
Zhixiang Xu
contact affiliationFudan University
contact emailzhixiangxu@fudan.edu.cn
lab head
Hong Li
contact affiliationFudan University
contact emailshenglihong@fudan.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI

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