PXD057615

PXD057615 is an original dataset announced via ProteomeXchange.

Title	Platelet-phenotypes in chronic inflammation
Description	In addition to their well-established role in thrombosis and hemostasis, there is growing evidence that platelets play a central role in systemic inflammatory processes. Therefore, we aimed to gain insights into the phenotype and possible platelet-subgroups in the context of different types of inflammation using psoriasis (type III inflammation) and atopic dermatitis (type II inflammation) as model diseases. Bulk proteomics were performed on platelets of a prospectively followed cohort of psoriasis/atopic dermatitis patients undergoing systemic therapy.
HostingRepository	PRIDE
AnnounceDate	2025-10-10
AnnouncementXML	Submission_2025-10-09_19:59:49.587.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Katharina Kommoss
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-07 03:33:12	ID requested
⏵ 1	2025-10-09 19:59:50	announced

Dataset with its publication pending

submitter keyword: Type 2 inflammation, platelets, psoriasis, type 3 inflammation, atopic dermatitis

Prof. Mathias
contact affiliation	Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany Institute for Interdisciplinary Research on Cancer Metabolism and Chronic Inflammation, The M3 Research Centre, Medical Faculty Tübingen, Germany
contact email	m.heikenwaelder@dkfz-heidelberg.de
lab head
Katharina Kommoss
contact affiliation	Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany
contact email	katharina.kommoss@med.uni-heidelberg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD057615

PRIDE project URI

• PRIDE
  1. PXD057615
     1. Label: PRIDE project
     2. Name: Platelet-phenotypes in chronic inflammation