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PXD057612

PXD057612 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSerum Disease-specific IgG Fc Glycosylation as Potential Biomarkers for Nonproliferative and Proliferative Diabetic Retinopathy Using Mass Spectrometry
DescriptionThe patients were enrolled and categorized into three groups according to clinical diagnosis: non-diabetic retinopathy; nonproliferative diabetic retinopathy ; and proliferative diabetic retinopathy. Gel electrophoresis was performed to separate IgG from morning fasting blood samples and polyaniline magnetic nanomaterials (Fe3O4@PANI) were used to enrich IgG N-glycopeptides from tryptic digestion. Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI ToF MS) was used to detect the IgG N-glycopeptides.
HostingRepositoryPRIDE
AnnounceDate2025-06-16
AnnouncementXMLSubmission_2025-06-15_16:05:41.401.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYishuang Mao
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentultrafleXtreme
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-11-07 02:31:13ID requested
12025-06-15 16:05:42announced
Publication List
Mao Y, Zhang J, Zhang Y, Hu B, Hao Y, Yuan Z, Zhao X, Wang Y, Wei Z, Yu W, Li Z, Serum Disease-Specific IgG Fc Glycosylation as Potential Biomarkers for Nonproliferative and Proliferative Diabetic Retinopathy Using Mass Spectrometry. Mol Cell Proteomics, 24(5):100967(2025) [pubmed]
10.1016/j.mcpro.2025.100967;
Keyword List
submitter keyword: IgG N-glycosylation, mass spectrometry, biomarkers., diabetic retinopathy
Contact List
Zhili Li
contact affiliationDepartment of Biophysics and Structural Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & School of Basic Medicine, Peking Union Medical College
contact emaillizhili@ibms.pumc.edu.cn
lab head
Yishuang Mao
contact affiliationPeking Union Medical College Hospital
contact emailmaoyishuang1999@126.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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