PXD057548

PXD057548 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Analyzing Intrinsically Ordered and Disordered Regions of the DDD Complex
Description	We used HDX-MS to analyze which regions of the DDD complex are intrinsically ordered and disordered. Deuterium incorporation after 3 seconds at zero degrees celsius was compared to deuterium incoporation in a fully deuterated sample. We were able to determine which componants of the DDD complex have the most stable and unstable secondary structure.
HostingRepository	PRIDE
AnnounceDate	2025-03-10
AnnouncementXML	Submission_2025-03-10_11:49:33.184.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	John Burke
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	impact HD

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-05 12:04:04	ID requested
⏵ 1	2025-03-10 11:49:34	announced

Publication List

10.1126/sciadv.adq4187;
Burgess AE, Loughran TA, Turk LS, Nyvall HG, Dunlop JL, Jamieson SA, Curry JR, Burke JE, Filipcik P, Brown SHJ, Mace PD, complexes. Sci Adv, 11(9):eadq4187(2025) [pubmed]

10.1126/sciadv.adq4187;

Burgess AE, Loughran TA, Turk LS, Nyvall HG, Dunlop JL, Jamieson SA, Curry JR, Burke JE, Filipcik P, Brown SHJ, Mace PD, complexes. Sci Adv, 11(9):eadq4187(2025) [pubmed]

Keyword List

submitter keyword: Ube2e2, DDA1,HDX-MS, DET1, DDB1

submitter keyword: Ube2e2, DDA1,HDX-MS, DET1, DDB1

Contact List

Dr. John E. Burke
contact affiliation	University of Victoria
contact email	jeburke@uvic.ca
lab head
John Burke
contact affiliation	University of Victoria
contact email	jeburke@uvic.ca
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/03/PXD057548
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/03/PXD057548

PRIDE project URI

Repository Record List

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