PXD057541

PXD057541 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Small molecule-induced alterations of protein polyubiquitination revealed by mass-spectrometric ubiquitome analysis
Description	Mammalian cells were treated with different small molecules which interfere with the ubiquitin system. After cell lysis, ubiquitinated proteins were enriched with biotin-tagged TUBE, digested with Trypsin/LysC and labelled with TMT. Peptides were fractionated at high pH before nano-LC-MS/MS analysis.
HostingRepository	MassIVE
AnnounceDate	2025-06-06
AnnouncementXML	Submission_2025-06-06_04:14:20.865.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Petra Janning
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-05 07:53:09	ID requested
⏵ 1	2025-06-06 04:14:21	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: Drug discovery, Ubiquitin proteasome system, Protein degradation, TMT labeling, Deubiquitinase inhibitors, DatasetType:Proteomics

submitter keyword: Drug discovery, Ubiquitin proteasome system, Protein degradation, TMT labeling, Deubiquitinase inhibitors, DatasetType:Proteomics

Contact List

Petra Janning
contact affiliation	MPI of Molecular Physiology
contact email	petra.janning@mpi-dortmund.mpg.de
lab head
Petra Janning
contact affiliation	MPI f�r molekulare Physiologie
contact email	petra.janning@mpi-dortmund.mpg.de
dataset submitter

Full Dataset Link List

MassIVE dataset URI
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MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v07/MSV000096295/