PXD057516

PXD057516 is an original dataset announced via ProteomeXchange.

Title	Reconstitution of Pluripotency from Mouse Fibroblast through Sall4 Overexpression
Description	We report that SALL4 alone, under an optimized reprogramming medium iCD4, is capable of reprogramming mouse fibroblasts into iPSCs. To identify SALL4-direct-interacting proteins, we performed immunoprecipitation followed by mass spectrometry (IP-MS) using MEFs overexpressing WT-SALL4 or SALL4 mutants (ΔZFC1, ΔZFC2, ΔZFC3, and ΔN12) at day 1.
HostingRepository	iProX
AnnounceDate	2024-11-05
AnnouncementXML	Submission_2025-08-21_18:59:00.855.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Lizhan Xiao
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-04 23:12:17	ID requested
1	2024-11-04 23:12:34	announced
⏵ 2	2025-08-21 18:59:01	announced	2025-08-22: Add info.

Xiao L, Huang Z, Wu Z, Yang Y, Zhang Z, Kumar M, Wu H, Mao H, Lin L, Lin R, Long J, Zeng L, Guo J, Luo R, Li Y, Zhu P, Liao B, Wang L, Liu J, Reconstitution of pluripotency from mouse fibroblast through Sall4 overexpression. Nat Commun, 15(1):10787(2024) [pubmed]

submitter keyword: iPSCs reprogramming, SALL4

Jing Liu
contact affiliation	Guangzhou Institutes of Biomedicine and Health
contact email	Liu_Jing@gibh.ac.cn
lab head
Lizhan Xiao
contact affiliation	Guangzhou Institutes of Biomedicine and Health
contact email	xiao_lizhan@163.com
dataset submitter

iProX dataset URI