PXD057514

PXD057514 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomics analysis of lysine methylated proteins from Leishmania donovani strain 1S: wild type and set mutants
Description	This study was performed with the goal of understanding the roles of Leishmania donovani SET7 and SET29 proteins. Using homologous recombination, set7 and set29 genes were knocked out, thereby creating set7 and set29 mutant parasites. Whole cell extracts were isolated from wild type parasites, set7 mutant parasites and set29 mutant parasites, followed by immunoprecipitation of lysine methylated proteins using anti-methyllysine antibody. The immunoprecipitated proteins were identified by LC-MS analysis.
HostingRepository	PRIDE
AnnounceDate	2025-01-24
AnnouncementXML	Submission_2025-01-24_00:19:22.789.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Swati Saha
SpeciesList	scientific name: Leishmania donovani; NCBI TaxID: 5661;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-04 22:46:52	ID requested
⏵ 1	2025-01-24 00:19:23	announced

Publication List

10.1016/j.jbc.2025.108208;
Sharma V, Pal J, Dashora V, Chattopadhyay S, Kapoor Y, Singha B, Arimbasseri GA, Saha S, The SET29 and SET7 proteins of Leishmania donovani exercise non-redundant convergent as well as collaborative functions in moderating the parasite's response to oxidative stress. J Biol Chem, 301(3):108208(2025) [pubmed]

10.1016/j.jbc.2025.108208;

Sharma V, Pal J, Dashora V, Chattopadhyay S, Kapoor Y, Singha B, Arimbasseri GA, Saha S, The SET29 and SET7 proteins of Leishmania donovani exercise non-redundant convergent as well as collaborative functions in moderating the parasite's response to oxidative stress. J Biol Chem, 301(3):108208(2025) [pubmed]

Keyword List

submitter keyword: SET proteins,Leishmania donovani, SET domain, lysine methylation

submitter keyword: SET proteins,Leishmania donovani, SET domain, lysine methylation

Contact List

Swati Saha
contact affiliation	Department of Microbiology, University of Delhi South Campus Benito Juarez Marg, South Campus, South Moti Bagh, New Delhi, Delhi 110021 India
contact email	ssaha@south.du.ac.in
lab head
Swati Saha
contact affiliation	Department of Microbiology, University of Delhi South Campus, New Delhi
contact email	swatisahalab@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/01/PXD057514
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/01/PXD057514

PRIDE project URI

Repository Record List

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