PXD057512

PXD057512 is an original dataset announced via ProteomeXchange.

Title	Tandem proteomic and N-glycoproteomic analysis of extracellular vesicles
Description	Extracellular vesicles (EVs) derived from diverse biofluids have emerged as promising noninvasive diagnostic biomarkers or signatures for various diseases. EV-associated N-glycoproteins are crucial for the biological functions of EVs and hold significant potential for disease diagnosis and prognosis. However, analyzing changes in EV N-glycoproteins from ultratrace samples presents considerable challenges. This study introduces a robust method, which utilizes magnetic nanochains to sensitively enrich EV N-glycoproteins in a single tube.
HostingRepository	iProX
AnnounceDate	2024-11-05
AnnouncementXML	Submission_2025-09-11_20:15:09.274.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Mingyang Li
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	deamidated residue
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-04 21:57:15	ID requested
1	2025-07-30 19:49:41	announced
⏵ 2	2025-09-11 20:15:10	announced	2025-09-12: Add info.

Li M, Song X, Tu H, Sun J, Deng Y, Wang B, Cai Y, Wang Y, Li B, Wang Y, Zhang X, Wei D, Yang X, Guo Y, Li X, Gu J, Ni J, Zhou Y, Gu Z, Xie Z, Li Y, Guo X, A functionally tunable magnetic nanochains platform for N-glycoproteomic analysis of extracellular vesicles from ultratrace biofluids. Nat Commun, 16(1):7646(2025) [pubmed]

submitter keyword: extracellular vesicles (EVs), N-glycopeptides, seminal plasma,asthenospermia (AZS), biofluid

Xuejiang Guo
contact affiliation	Nanjing Medical University
contact email	guo_xuejiang@njmu.edu.cn
lab head
Mingyang Li
contact affiliation	Southeast University
contact email	230229239@seu.edu.cn
dataset submitter

iProX dataset URI