PXD057442 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | What does next generation Mass Spectrometry offer for proteomics? A comprehensive platform comparison |
| Description | Next-generation mass spectrometry platforms (Orbitrap Astral, timsTOF Ultra) are reshaping proteomics by enhancing analytical depth and sensitivity. We compared these platforms against Orbitrap Exploris 480 using neonatal mouse lung tissue from a bronchopulmonary dysplasia model (n=12), employing four acquisition strategies: Exploris 480 DDA/DIA, Astral HR-DIA, and timsTOF Ultra DIA-PASEF. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-04-02 |
| AnnouncementXML | Submission_2026-04-02_15:16:55.298.xml |
| DigitalObjectIdentifier | https://doi.org/10.6019/PXD057442 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Filipa Blasco Tavares Pereira Lopes |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2024-11-01 16:54:15 | ID requested | |
| ⏵ 1 | 2026-04-02 15:16:56 | announced | |
Publication List
| Blasco Tavares Pereira Lopes F, Schlatzer D, Sudhadevi T, Harijith A, Ayati M, Koyut, ΓΌ, rk M, Chance MR, What Does Next-Generation Mass Spectrometry Offer for Proteomics? A Comprehensive Platform Comparison. J Proteome Res, 25(4):1929-1940(2026) [pubmed] |
| 10.1021/acs.jproteome.5c01007; |
| 10.6019/PXD057442; |
Keyword List
| submitter keyword: Mouse, Lung, Bronchopulmonary Dysplasia, Platform Comparison |
Contact List
| Mark Chance |
|---|
| contact affiliation | Department of Nutrition, Center for Proteomics and Bioinformatics, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA; Case Center for Synchrotron Biosciences, Brookhaven National Laboratory, Upton, New York, USA |
| contact email | mark.chance@case.edu |
| lab head | |
| Filipa Blasco Tavares Pereira Lopes |
|---|
| contact affiliation | Department of Nutrition, Center for Proteomics and Bioinformatics, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA |
| contact email | fxb99@case.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD057442 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD057442
- Label: PRIDE project
- Name: What does next generation Mass Spectrometry offer for proteomics? A comprehensive platform comparison
