PXD057410

PXD057410 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Affinity purification of HA-tagged Chromodomain helicase DNA-binding protein 6 in HEK293T cells
Description	Affinity purification and mass spectrometry analysis of HA-tagged CHD6 protein overexpressed in HEK293T cells.
HostingRepository	PRIDE
AnnounceDate	2025-05-07
AnnouncementXML	Submission_2025-05-07_04:30:45.798.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD057410
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Luc Provencher
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-10-31 14:55:07	ID requested
⏵ 1	2025-05-07 04:30:46	announced

Publication List

Provencher L, Nartey W, Brownlee PM, Atkins AW, Gagn, é JP, Baudrier L, Ting NSY, Piett CG, Fang S, Pearson DD, Moore S, Billon P, Nagel ZD, Poirier GG, Williams GJ, Goodarzi AA, CHD6 has poly(ADP-ribose)- and DNA-binding domains and regulates PARP1/2-trapping inhibitor sensitivity via abasic site repair. Nat Commun, 16(1):1026(2025) [pubmed]
10.6019/PXD057410;
10.1038/s41467-025-56085-5;

Provencher L, Nartey W, Brownlee PM, Atkins AW, Gagn, é JP, Baudrier L, Ting NSY, Piett CG, Fang S, Pearson DD, Moore S, Billon P, Nagel ZD, Poirier GG, Williams GJ, Goodarzi AA, CHD6 has poly(ADP-ribose)- and DNA-binding domains and regulates PARP1/2-trapping inhibitor sensitivity via abasic site repair. Nat Commun, 16(1):1026(2025) [pubmed]

10.6019/PXD057410;

10.1038/s41467-025-56085-5;

Keyword List

submitter keyword: Human, Overexpression, AP-MS, LC-MSMS, RIME, Cells

submitter keyword: Human, Overexpression, AP-MS, LC-MSMS, RIME, Cells

Contact List

Aaron Goodarzi
contact affiliation	Department of Biochemistry and Molecular Biology Charbonneau Research Institute Cummings School of Medicine University of Calgary
contact email	a.goodarzi@ucalgary.ca
lab head
Luc Provencher
contact affiliation	University of Calgary
contact email	luc.provencher@ucalgary.ca
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD057410
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD057410

PRIDE project URI

Repository Record List

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