PXD057331
PXD057331 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | A Full Window Data Independent Acquisition Method for Deeper Top-down Proteomics |
| Description | In this study, we present a novel Full Window DIA (FW-DIA) method designed to address the challenges associated with data-independent acquisition in top-down proteomics. The FW-DIA approach significantly enhances fragment signal intensities by approximately 50-fold and increases protein sequence coverage threefold. The efficacy of FW-DIA was demonstrated through the analysis of a five-protein mixture under native conditions, as well as ribosomal proteins from Escherichia coli (E. coli). |
| HostingRepository | iProX |
| AnnounceDate | 2024-10-30 |
| AnnouncementXML | Submission_2024-10-29_20:55:31.726.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Chen Sun |
| SpeciesList | scientific name: Escherichia coli; NCBI TaxID: 562; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Xevo G2-S QTof |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-10-29 20:54:12 | ID requested | |
| ⏵ 1 | 2024-10-29 20:55:32 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: top-down proteomics, data-independent analysis, mass spectrometry |
Contact List
| Wei Xu | |
|---|---|
| contact affiliation | Beijing Institute of Technology |
| contact email | weixu@bit.edu.cn |
| lab head | |
| Chen Sun | |
| contact affiliation | Beijing Institute of Technology |
| contact email | 3120225721@bit.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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