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PXD057301

PXD057301 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProximity proteomics of phagophore-associated proteins using APEX2-LC3B in VPS37A KO U-2 OS cells
DescriptionWe utilized an APEX2-mediated proximity biotinylation approach to label proteins on LC3-positive membranes that accumulate in VPS37A-knockout (KO) U-2 OS cells. AP, APEX2 control; WT, APEX2-LC3B.
HostingRepositoryPRIDE
AnnounceDate2024-12-03
AnnouncementXMLSubmission_2024-12-03_06:59:27.721.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD057301
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterYoshinori Takahashi
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
Instrumentautoflex
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-10-29 10:33:32ID requested
12024-12-03 06:59:28announced
Publication List
10.6019/PXD057301;
10.1016/j.celrep.2024.115016;
Hamamoto K, Liang X, Ito A, Lanza M, Bui V, Zhang J, Opozda DM, Hattori T, Chen L, Haddock D, Imamura F, Wang HG, Takahashi Y, Unveiling the physiological impact of ESCRT-dependent autophagosome closure by targeting the VPS37A ubiquitin E2 variant-like domain. Cell Rep, 43(12):115016(2024) [pubmed]
Keyword List
submitter keyword: Human, VPS37A KO U-2 OS cells, Autophagosomal membrane, Phagophore, APEX2-LC3B
Contact List
Yoshinori Takahashi
contact affiliationDivision of Pediatric Hematology and Oncology, Department of Pediatrics, The Pennsylvania State University College of Medicine
contact emailytakahashi@pennstatehealth.psu.edu
lab head
Yoshinori Takahashi
contact affiliationThe Pennsylvania State University
contact emailytakahashi@pennstatehealth.psu.edu
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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