PXD057287 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Acetylome analysis of HepG2 cells after treatment with PBS or LukS-PV |
| Description | We previously reported that LukS-PV, a component of Panton-Valentine interleukin (PVL), has anti-leukaemic activity, inducing differentiation, increasing apoptosis and inhibiting proliferation of acute myeloid leukaemia (AML) cells. In addition, our study showed that LukS-PV could inhibit the progression of hepatocellular carcinoma (HCC) by targeting C5aR. To investigate the biological mechanisms involved, we performed acetylome analysis on PBS/LukS-PV-treated HCC cells to search for important downstream regulators. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-01-02 |
| AnnouncementXML | Submission_2026-01-01_23:59:09.323.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Xiaoling Ma |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | acetylated residue |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2024-10-29 07:12:00 | ID requested | |
| ⏵ 1 | 2026-01-01 23:59:09 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: LukS-PV |
| HepG2 |
| acetylome analysis |
| LC-MS/MS |
Contact List
| Xiaoling Ma |
|---|
| contact affiliation | Department of Clinical Laboratory, The First Affiliated Hospital of University of Science and Technology of China (USTC), Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. |
| contact email | maxiaoling@ustc.edu.cn |
| lab head | |
| Xiaoling Ma |
|---|
| contact affiliation | The First Affiliated Hospital of University of Science and Technology of China (USTC) |
| contact email | maxiaoling@ustc.edu.cn |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD057287 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD057287
- Label: PRIDE project
- Name: Acetylome analysis of HepG2 cells after treatment with PBS or LukS-PV
