PXD057203

PXD057203 is an original dataset announced via ProteomeXchange.

Title	Identification of mitochondrial Cyclophilins
Description	We aimed at identify variants of the mitochondrial Cyclophilin D from total lysates of human skin fibroblasts and murine tissues. Total lysates were loaded onto SDS-PAGE stained with MS-compatible Coomassie and bands around 19 and 18 kDa were manually excised. In fact in Western blots analysis of CyPD, which is the sole known mitochondrial Cyclophilin, often show two distinct bands at that molecular weights.
HostingRepository	PRIDE
AnnounceDate	2025-05-07
AnnouncementXML	Submission_2025-05-07_03:56:59.194.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Gabriele Coluccino
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2024-10-25 08:10:34	ID requested
⏵ 1	2025-05-07 03:57:00	announced

10.1038/s42003-024-07172-8;

Coluccino G, Negro A, Filippi A, Bean C, Muraca VP, Gissi C, Canetti D, Mimmi MC, Zamprogno E, Ciscato F, Acquasaliente L, De Filippis V, Comelli M, Carraro M, Rasola A, Gerle C, Bernardi P, Corazza A, Lippe G, N-terminal cleavage of cyclophilin D boosts its ability to bind F-ATP synthase. Commun Biol, 7(1):1486(2024) [pubmed]

submitter keyword: Human, Murine, CyPD, mitochondria, ppif

Alessandra Corazza
contact affiliation	University of Udine - DMED
contact email	alessandra.corazza@uniud.it
lab head
Gabriele Coluccino
contact affiliation	Department of Medicine, University of Udine
contact email	gabriele.coluccino@uniud.it
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD057203

PRIDE project URI

• PRIDE
  1. PXD057203
     1. Label: PRIDE project
     2. Name: Identification of mitochondrial Cyclophilins