PXD057151
PXD057151 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Orofiamma_AMPK_Arf6_TripleTOF6600_P116 |
| Description | This dataset consists of 18 raw MS files and associated peak lists and results files, acquired on a ABSCiex TripleTOF6600 operated in Data Dependent Acquisition mode. Sample generation and affinity purification was performed by Geoffrey Hesketh. Mass spectrometry acquisition was performed by Geoffrey Hesketh. Analysis was performed by Geoffrey Hesketh, Laura Orofiamma, Anne-Claude Gingras, and Costin Antonescu. The files are associated with a manuscript submitted for publication by Laura Orofiamma et al. This dataset identifies proximity-dependent interactions of ARF6 in wildtype, GDP-locked and GTP-locked states using BioID in HeLa cells. The associated manuscript identifies AMPK as a regulator of cargo-specific clathrin-dependent endocytosis dynamics, which acts through ARF6 regulation. Costin Antonescu is the corresponding author of the manuscript (cantonescu@torontomu.ca); Anne-Claude Gingras should be contacted for questions on this dataset (gingras@lunenfeld.ca) This submission is associated with 2 Supplementary Files (in addition to this README file) Table 1 describes the composition of this dataset Table 2 lists all the peptide identification evidence Table 3 lists the SAINTexpress interactions |
| HostingRepository | MassIVE |
| AnnounceDate | 2025-06-06 |
| AnnouncementXML | Submission_2025-06-06_05:32:50.420.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Gingras Lab |
| SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
| ModificationList | deamidated L-asparagine; deamidated L-glutamine; L-methionine sulfoxide |
| Instrument | TripleTOF 6600 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-10-24 05:25:44 | ID requested | |
| ⏵ 1 | 2025-06-06 05:32:50 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: BioID, Proximity-dependent biotinylation, Arf6, AMPK, clathrin-dependent endocytosis, DatasetType:Proteomics |
Contact List
| Anne-Claude Gingras | |
|---|---|
| contact affiliation | LTRI |
| contact email | gingras@lunenfeld.ca |
| lab head | |
| Gingras Lab | |
| contact affiliation | Samuel Lunenfeld Research Institute |
| contact email | gingras@mshri.on.ca |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v07/MSV000096190/ |
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